2025/26 Europa League Round of 16 Draw - Outright Betting Odds & Predictions
The 2025/26 UEFA Europa League Round of 16 draw has set the stage for an exciting phase of competition, with Aston Villa favored in the betting markets. The schedule reveals fierce matchups: Braga is poised against Ferencvaros, Real Betis faces Panathinaikos, and Genk battles Freiburg. Aston Villa, facing potential challenges from Roma and Nottingham Forest, leads the odds for eventual victory. Lyon presents strong value from the upper draw, with bookmakers tipping them as serious contenders. This stage paves a thrilling road towards the final at Besiktas Stadium.
- The 2025/26 Europa League is down to the last 16
- Aston Villa leads the betting market with Roma & Lyon next best
The 2025/26 UEFA Europa League Round of 16 draw has concluded and the path to the final at Besiktas Stadium mapped out.
The upper bracket is expected to be dominated by Lyon while the lower bracket features tournament favourites Aston Villa.
Here is the complete schedule for the Round of 16 ties, followed by a breakdown of all eight matchups and what they mean for the outright winner market.
2025/26 Europa League Round of 16 Schedule
| Team 1 | Tie | Team 2 | 1st Leg | KO (CET) |
2nd Leg | KO (CET) |
|---|---|---|---|---|---|---|
| Ferencvaros | 1 | Braga | 12 March | 21:00 | 19 March | 16:30 |
| Panathinaikos | 2 | Real Betis | 12 March | 18:45 | 19 March | 21:00 |
| Genk | 3 | Freiburg | 12 March | 21:00 | 19 March | 18:45 |
| Celta Vigo | 4 | Lyon | 12 March | 21:00 | 19 March | 18:45 |
| Stuttgart | 5 | Porto | 12 March | 18:45 | 19 March | 21:00 |
| Nottingham Forest | 6 | Midtjylland | 12 March | 21:00 | 19 March | 18:45 |
| Bologna | 7 | Roma | 12 March | 18:45 | 19 March | 21:00 |
| Lille | 8 | Aston Villa | 12 March | 18:45 | 19 March | 21:00 |
Ferencvaros vs Braga
Braga reached the Europa League final in 2011 and will be huge favorites to get past Ferencvaros.
Panathinaikos vs Real Betis
Real Betis lost the Conference League final last season and Panathinaikos survived a penalty shootout to get past Viktoria Plzen in the playoffs. Betis are heavy favorites to advance.
Genk vs Freiburg
Genk showed immense resilience to scrape past Dinamo Zagreb in playoffs and face a tougher challenge in Freiburg.
Celta Vigo vs Lyon
Lyon dominated the league phase to finish top of the table and are heavily backed in the outright markets. Celta Vigo are a tricky test but should have enough quality to get through.
Stuttgart vs Porto
Stuttgart beat Celtic on aggregate despite losing 1-0 at home in the second leg. Porto sit top of the table in Portugal after an impressive campaign under Francisco Farioli but face a tough test against the German club.
Nottingham Forest vs Midtjylland
Forest got past Fenerbahce 4-2 on aggregate following a dominant 3-0 first leg victory in Turkey. New manager Vitor Pereira will be please with a tie against Midtjylland, arguably the weakest of the seeded teams.
Bologna vs Roma
An all-Italian clash, Roma know how to navigate deep European runs while Bologna are riding the momentum of last season's Coppa Italia victory.
Lille vs Aston Villa
Aston Villa who finished second to Lyon in the league phase and are the bookmakers' favorites to lift the trophy in May. Lille secured an extra time win over Crvena Zvezda to reach the round of 16.
2025/26 Europa League Winner Betting Odds
Aston Villa lead the way in the betting market but won't have an easy run to the final with Roma, Nottingham Forest, Stuttgart and Porto likely to stand in their way.
The top half of the draw offers more value with Lyon most likely to contest the showpiece in Istanbul.
| Team | Odds |
|---|---|
| Aston Villa |
3.75 |
| Roma |
8.00 |
| Lyon |
9.00 |
| Nottingham Forest |
9.00 |
| Porto |
10.00 |
| Real Betis |
11.00 |
| Bologna |
11.00 |
| Stuttgart |
13.00 |
| SC Freiburg |
21.00 |
| Celta Vigo |
21.00 |
| Lille |
26.00 |
| Braga |
29.00 |
| Genk |
34.00 |
| Midtjylland |
41.00 |
| Ferencvaros |
41.00 |
| Panathinaikos |
51.00 |
Verdict
It's easy to see why Aston Villa are the favourites but I am going to fade the English club. Roma have a quality side and Lyon should have enough quality to get though the top half of the draw.
Roma Win
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Lyon Win
Winner
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