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Detroit Tigers at Chicago White Sox Betting Tips – Over To Cash In Windy City MLB Clash

leigh-copson
Editor
Last updated: Fri 18 Sep 2026 08:40
The upcoming game between the Detroit Tigers and Chicago White Sox features struggling pitchers on both sides: Detroit’s Andrew Sears (0-1, 5.40 ERA) and Chicago’s David Sandlin (2-2, 5.64 ERA). While Detroit leads the all-time series, the White Sox won the last matchup and Detroit has lost 12 of their last 16 road games. Recent forms show mixed results for both. With both pitchers being vulnerable, the recommended bet is the Over, anticipating plenty of runs scored, though there’s a slight lean towards the White Sox for the win.
Leigh Copson 18 Sep 2026
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  • Both starting pitchers have ERAs above 5.00 and are hittable
  • Tigers have lost 12 of their last 16 road games; White Sox won last meeting
  • Best bet: Over on total runs; lean toward White Sox for the win
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(Getty Images)

The Over is tipped to cash in the second game of this series.

Both pitchers have proven to be very hittable in their limited action this season, so the runs could pile up in this one.

Key Numbers – Will Tigers Suffer 13th Loss In 17 Road Games?

  • Detroit Tigers have lost 12 of their last 16 road games
  • Detroit starter Andrew Sears is 0-1 with a 5.40 ERA
  • Chicago pitcher David Sandlin is 2-2 with a 5.64 ERA

Tigers Lead All-Time Head-To-Head; White Sox Won Last Meeting

  • Detroit Tigers lead the all-time series 1149-1121-15
  • Chicago White Sox won 3-1 when the two teams last met on September 17

Detroit Tigers Form – Last 10 Games

Detroit enter the second game of this series having won seven of their last 10 games, but having lost their last two.

DateOppositionW/LScore
Sep-07 vs Minnesota Twins W 5-4
Sep-08 vs Minnesota Twins L 2-3
Sep-09 vs Minnesota Twins W 7-2
Sep-11 vs Colorado Rockies W 6-2
Sep-12 vs Colorado Rockies W 11-7
Sep-13 vs Colorado Rockies W 8-1
Sep-14 at Toronto Blue Jays W 6-5
Sep-15 at Toronto Blue Jays W 10-1
Sep-16 at Toronto Blue Jays L 1-5
Sep-17 at Chicago White Sox L 1-3

Chicago White Sox Form – Last 10 Games

Chicago go into this matchup having snapped a two-game losing sequence last night, but having lost seven of their previous 10 games.

DateOppositionW/LScore
Sep-08 vs Pittsburgh Pirates L 3-9
Sep-09 vs Pittsburgh Pirates L 2-4
Sep-10 vs Pittsburgh Pirates L 0-2
Sep-11 at St Louis Cardinals L 3-7
Sep-12 at St Louis Cardinals W 6-5
Sep-13 at St Louis Cardinals L 1-3
Sep-14 at Cleveland Guardians W 7-3
Sep-15 at Cleveland Guardians L 6-7 W/O
Sep-16 at Cleveland Guardians L 3-6
Sep-17 vs Detroit Tigers W 3-1

Starting Pitchers

PlayerTeamRecordERAStrikeoutsInnings
Andrew Sears Detroit Tigers 0-1 5.40 13 16.2
David Sandlin Chicago White Sox 2-2 5.6429 30.1

Verdict

Detroit’s recent struggles on the road continued, so we are leaning towards the White Sox in this one.

However, the more appealing bet is the Over – these two pitchers have been lit up several times in their limited innings.

Best Bet1: Over 8.5 Total Runs @9/10 at bet365 - 4 Units
Best Bet2: Chicago Win Moneyline @8/11 at dabble - 2 Units
Over 8.5
Total Runs
@9/10 - 4 Units
Bet £10 Get £30
with bonus code NEWBONUS

Available to new customers only. Make a qualifying deposit of £5 or more and claim the offer within 30 days of registering your account to qualify for 300% of that amount in Bet Credits, up to a maximum of £30 in Bet Credits. Once released, your Bet Credits will be held in your account balance and are non-withdrawable. Min deposit requirement. Free Bets are paid as Bet Credits and are available for use upon settlement of qualifying bets. Min odds, bet and payment method exclusions apply. Returns exclude Bet Credits stake. Registration required. Time limits and T&Cs apply. The bonus code NEWBONUS can be used during registration but does not change the offer amount in any way. #ad

Bet at bet365
Chicago Win
Moneyline
@8/11 - 2 Units
Bet £10 Get £10
Promo Code: NEWBONUS

New customers only. Bet £10+ to receive £10 in Free Bets. 7-day free bet expiry. Stake not returned. Promotional Terms Apply. 18+. GambleAware.org

Bet at dabble
leigh-copson
Leigh Copson

Sports Editor • 25+ Years Experience, US & Combat Sports Specialist

US sports writer covering the NFL, NBA, NHL, boxing and MMA, with previews, predictions and betting tips across the major American leagues.

During his career at the Press Association and online sports sites including FreeTips and ExpertPicks.com, he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final.

He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.

Follow more of Leigh's work on Muckrack and connect with him on LinkedIn.

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