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Illinois at Ohio State Betting Tips – Back Buckeyes To Cover Big College Football Spread

leigh-copson
Editor
Last updated: Mon 21 Sep 2026 15:23
Ohio State are expected to cover the spread as double-digit favorites when they host Illinois. Historically dominant at home, the Buckeyes have covered in 9 of their last 11 games as significant favorites, while Illinois have struggled both as road underdogs and in covering spreads. Both teams bring 2-1 records, but Ohio State's offense has looked particularly strong following a bounce-back win over Kent State. Recommendation: Back Ohio State to cover the spread in another high-scoring, one-sided contest.
Leigh Copson 1 hour ago
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  • Ohio State has covered in 9 of last 11 as double-digit favourites
  • Illinois has struggled to cover on the road and as underdogs
  • Expect another high-scoring Buckeyes win and to cover the spread
(Getty Images)

Ohio State are tipped to cover as they record another home blowout.

The Buckeyes have been dominant at home so far, and have routinely covered as a double digit favourite over the past couple of seasons.

Key Numbers – Will Buckeyes Cover Again As Double Digit Favourite?

  • Ohio State have covered in 9 of their last 11 games as a double digit favourite
  • Illinois have failed to cover in 2 of their 3 games so far this season
  • Illinois failed to cover in their 2 games as a road betting underdog last season
  • The Over has cashed in 5 of the 6 games involving either team this season

Ohio State Lead All-Time Head-To-Head; Won Last Meeting

  • Ohio State lead the all-time series 19-8
  • Ohio State won 34-16 when the two teams last met in October 2025

Illinois Take 2-1 Record To Ohio State

Illinois head out on the road for the first time this season having bounced back from a defeat to improve to 2-1.

The Fighting Illini kicked off their campaign at home to UAB, and ran out 42-23 winners against the Blazers.

They failed to follow that up a week later as they lost 31-27 to Duke, but they issued an immediate response last weekend, albeit against weaker opposition.

Illinois eased to a 48-10 win over Southern Illinois, with quarterback Katin Houser going 23/29 for 305 yards, two touchdowns and an interception.

Collin Dixon racked up 131 yards and two receiving touchdowns, while Adam Laughery turned four carries into 93 yards and a touchdown.

Ohio State Bounced Back From Texas Defeat

Ohio State go into their Big Ten opener having rebounded from the loss in Texas to take their record to 2-1.

The Buckeyes made light work of their opening game of the season, as they blew out Ball State at home, 56-3.

They failed to follow that up a week later though, as they lost an eagerly-awaiting road game against Texas, 24-23.

Ohio State were quick to put that defeat behind them however, as Julian Sayin went 18/22 for 241 yards and two touchdowns in a 59-3 rout of Kent State.

Jeremiah Smith finished the game with 85 receiving yards, while Bo Jackson ran for 73 yards and a score.

Verdict

Ohio State made light work of Kent State a week ago, and we expect another one-sided win here.

This red-hot Buckeyes offense can pile up the points as they pull away to win the game and cover the spread.

Best Bet1: Ohio State -27.5 Spread @9/10 at bet365 - 4 Units
Best Bet2: Over 53.5 Total Points @9/10 at dabble - 2 Units
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leigh-copson
Leigh Copson

Sports Editor • 25+ Years Experience, US & Combat Sports Specialist

US sports writer covering the NFL, NBA, NHL, boxing and MMA, with previews, predictions and betting tips across the major American leagues.

During his career at the Press Association and online sports sites including FreeTips and ExpertPicks.com, he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final.

He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.

Follow more of Leigh's work on Muckrack and connect with him on LinkedIn.

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