• Home
  • American Football

Notre Dame at Purdue Betting Tips – Irish To Deliver Boilermaker Beatdown In College Football

leigh-copson
Editor
Last updated: Tue 22 Sep 2026 11:41
Notre Dame are heavily favored to cover the spread against Purdue as they look to build on their 3-0 start and sustain an impressive winning streak in the head-to-head series. The Fighting Irish's potent run game, led by Nolan James Jr, is expected to exploit Purdue's weak rush defense, while their own defense should slow down Purdue's high-powered offense. Despite Purdue's offensive efforts, particularly from QB Ryan Browne and WR Xavier Townsend, Notre Dame's balanced attack and defensive strength make them strong favorites to both win and cover.
Leigh Copson 1 hour ago
Share this article
Or copy link
  • Notre Dame is 3-0 and favoured to cover against Purdue
  • Fighting Irish have won the last 10 meetings
  • Purdue's offense is strong, but defense lags behind Notre Dame's
(Getty Images)

Notre Dame are tipped to cover a big spread as they down Purdue on the road.

The Fighting Irish can run all over this bad Boilermarker rush defense, while the visitors’ own defense puts the clamps on the home offense and forces key turnovers.

Key Numbers – Will Fighting Irish Record 3rd Cover?

  • Notre Dame have covered in 2 of their first 3 games
  • Notre Dame have won each of the previous 10 meetings
  • Notre Dame have covered against Purdue in each of the last 2 seasons
  • The Over has cashed in each of the last 2 meetings

Notre Dame Lead All-Time Head-To-Head; Won Last Meeting

  • Notre Dame lead the all-time series 61-26-2
  • Notre Dame won 56-30 when the two teams last met in September 2025

Notre Dame Take 3-0 Record On The Road

Notre Dame face Big Ten opposition for the second weekend in a row, looking to improve their record to 4-0.

The Fighting Irish kicked off the season by visiting Lambeau Field for a showdown with Wisconsin, which they won 41-13.

They followed that up with a shutout victory in their home opener a week later, beating Rice 52-0.

Notre Dame than made it three-in-a-row last weekend, as they downed Michigan State, 27-10, in South Bend.

Running back Nolan James Jr did the damage on the ground as he rushed for 121 yards and a touchdown.

Purdue Sit 1-2 Following Back-To-Back Defeats

Purdue go into Saturday’s game having failed to build on a season-opening win, losing back-to-back games.

The Boilermakers opened the campaign at home and enjoyed a successful start as they downed Indiana State 44-19.

They failed to follow that up a week later though, as they suffered a narrow 38-36 defeat at the hands of Wake Forest.

It then became consecutive losses for Purdue last weekend, as they were beaten 52-38 by UCLA in their road opener.

Quarterback Ryan Browne went 19/30 for 378 yards, three touchdowns and an interception, with Xavier Townsend hauling in six catches for 162 yards and two scores.

Verdict

Purdue’s offense has been rolling despite back-to-back losses, but this Notre Dame defense is capable of slowing down the Boilermakers attack.

And on the opposite side of the football, the Fighting Irish can put the ball in the hands of Carr and James Jr to ensure they pull away, win the game and cover the spread.

Best Bet1: Notre Dame -27.5 Spread @9/10 at bet365 - 4 Units
Best Bet2: Over 57.5 Total Points @9/10 at dabble - 2 Units
Notre Dame -27.5
Spread
@9/10 - 4 Units
Bet £10 Get £30
with bonus code NEWBONUS

Available to new customers only. Make a qualifying deposit of £5 or more and claim the offer within 30 days of registering your account to qualify for 300% of that amount in Bet Credits, up to a maximum of £30 in Bet Credits. Once released, your Bet Credits will be held in your account balance and are non-withdrawable. Min deposit requirement. Free Bets are paid as Bet Credits and are available for use upon settlement of qualifying bets. Min odds, bet and payment method exclusions apply. Returns exclude Bet Credits stake. Registration required. Time limits and T&Cs apply. The bonus code NEWBONUS can be used during registration but does not change the offer amount in any way. #ad

Bet at bet365
Over 57.5
Total Points
@9/10 - 2 Units
Bet £10 Get £10
Promo Code: NEWBONUS

New customers only. Bet £10+ to receive £10 in Free Bets. 7-day free bet expiry. Stake not returned. Promotional Terms Apply. 18+. GambleAware.org

Bet at dabble
leigh-copson
Leigh Copson

Sports Editor • 25+ Years Experience, US & Combat Sports Specialist

US sports writer covering the NFL, NBA, NHL, boxing and MMA, with previews, predictions and betting tips across the major American leagues.

During his career at the Press Association and online sports sites including FreeTips and ExpertPicks.com, he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final.

He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.

Follow more of Leigh's work on Muckrack and connect with him on LinkedIn.

Read More

Top Betting Sites

special-offer-1Betting offers

Upcoming Events

26 Sep 2026

Notre Dame @ Purdue

days

hours

min

Add to Calendar
Hear more from Freetips.com