Anderlecht vs Lyon Tips & Predictions – Both Sides to Score in the Europa League

Vedran Ostojic

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Last updated: Mon 14 Sep 2026 15:37

Vedran Ostojic 1 hour ago

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Both teams have a pattern of high-scoring European games
We are backing both Anderlecht and Lyon to find the net
Check our full preview for Anderlecht vs Lyon below

Anderlecht have seen over 2.5 goals in 4 of their last 5 UEL matches (Getty)

18 goals were scored in Anderlecht's six Europa League games this season, while Lyon also scored in all four UCL qualifying contests. I am predicting both sides to score on Wednesday.

Key Stats
Les Gones Lead Head to Head
Anderlecht Looked Great in the Qualifiers
Lyon Unbeaten in France
Team News & Predicted Lineups

Key Stats

Anderlecht have seen over 2.5 goals in 4 of their last 5 matches (Europa League).
Lyon have seen BTTS in 3 of their last 4 matches.

Les Gones Lead Head to Head

This is going to be the fifth time these two teams lock horns, and Lyon have a 3-1 advantage in terms of victories.

Anderlecht Looked Great in the Qualifiers

Anderlecht faced some tough opposition in the Europa League qualifiers but made it to the main stage. Their journey started in late July, eliminating Hammarby 4-2 and PAOK 4-2 on aggregate.

In the playoffs, the Belgian side crushed Kairat Almaty 6-0 on aggregate, securing 3-0 victories on the road and at home. Danylo Sikan appeared on the scoresheet on both occasions.

Vitor Bruno's side is also doing great in the Pro League this month, claiming seven points from the last three encounters. They defeated Kortrijk 1-0 and Mechelen 1-0, while the clash against Genk ended without goals.

Lyon Unbeaten in France

Lyon started their European journey in the UCL where they eliminated Sparta Prague 4-2 on aggregate, but were stopped by Fenerbahce in the final round, losing 3-2 on aggregate.

Paulo Fonseca's side is unbeaten after four rounds in the new Ligue 1 season, grabbing eight out of possible twelve points so far.

Victories were earned against Toulouse 2-0 and Auxerre 3-1, while being held to draws by underdogs Le Havre 1-1 and Paris FC 0-0.

Team News & Predicted Lineups

Anderlecht (4-4-2) Colin Coosemans; Ali Maamar, Giulian Biancone, Leo Petrot, Ludwig Augustinsson; Ilias Koutsoupias, Marco Kana, Marten Winkler, Oliver Antman; Tawfik Bentayeb, Danylo Sikan

The hosts must alter their squad setup due to several key absences, with Lucas Hey, Killian Sardella, and Ilay Camara remaining sidelined through injury.

Lyon (4-3-2-1) Dominik Greif; Zachary Athekame, Felix Bacher, Clinton Mata, Tanner Tessmann; Mads Bidstrup, Tyler Morton, Corentin Tolisso; Ernest Nuamah, Keito Nakamura; Lois Openda

Lyon have traveled to Belgium managing a heavily depleted squad, missing Julien Duranville, Moussa Niakhate, Abner Vinicius, and Ainsley Maitland-Niles alongside several doubts.

Verdict

Anderlecht v Lyon

When it comes to their European appearances, both sides were involved in plenty of high-scoring affairs, especially Anderlecht. BTTS is the standout selection here.

BTTS Yes

Both Teams to Score

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Vedran is a passionate sports enthusiast and covers European football, basketball, volleyball and handball.

With a particular love for the English Premier League, he's been writing about sports online for more than a decade since completing a degree in literature and sports journalism.

The primary areas of focus include top European football leagues (mainly EPL, La Liga, Serie A & Bundesliga), basketball (EuroLeague, NBA & WNBA), Handball and Volleyball.

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