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San Francisco 49ers at Seattle Seahawks Betting Tips – Seahawks To End 49ers’ NFL Playoffs Run

leigh-copson
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Last updated: Tue 13 Jan 2026 14:37
The Seattle Seahawks are poised to continue their success in the NFC West showdown against the San Francisco 49ers, having recently defeated the 49ers in the Week 18 matchup. Seattle, who lead the all-time series and are riding a seven-game win streak, appear fresh and ready, whereas the 49ers are dealing with the significant injury of George Kittle. Despite this setback, San Francisco boasts an impressive track record, having won seven of their last eight games. The Seahawks’ previous victories and healthier roster give them an edge for this upcoming playoff battle.
Leigh Copson 13 Jan 2026
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  • Seattle Seahawks carry 7-game win streak into playoffs
  • Key injury to 49ers' George Kittle adds pressure
  • Seahawks' recent success against 49ers a potential advantage
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Seattle are tipped to cover as they win this all-NFC West showdown in the playoffs.

San Francisco have done a tremendous job navigating injuries this season, but they just lost another key piece in George Kittle and how much more can they really take?

The Seahawks are fresh and healthy, and they can grind out another win over the 49ers like they did in Week 18.

Key Numbers – Can Seahawks Notch 15th Win?

  • Seattle Seahawks have won 14 of their 17 games
  • San Francisco 49ers have failed to cover in 2 of their last 3 games
  • The Under cashed during the 2 regular season meetings
  • The Under has hit in 4 of Seattle’s last 6 games against NFC West teams

Seahawks Lead All-Time Head-To-Head; Won Last Meeting

  • Seattle Seahawks lead the all-time series 32-24
  • Seattle Seahawks won 13-3 when the two teams last met on January 3

San Francisco 49ers Have Won 7 Of Last 8

San Francisco head to Seattle having ousted defending champions Philadelphia in the Wild Card round, making it seven wins in eight games.

The 49ers kicked off the campaign with a three-game win streak, but an inconsistent run over the next several weeks left them 6-4 in early November.

The found some form after that though, and went into the bye week having sandwiched a 20-9 win at home to Carolina with road successes at Arizona, 41-22, and Cleveland, 26-8.

San Francisco picked up from where they left off when they returned to action, extending their win streak to six games as they beat Tennessee 37-24 at home, Indianapolis 48-27 on the road and Chicago 42-38 at home.

That set up a huge showdown with Seattle on the final day of the regular season, when a 13-3 defeat cost the 49ers the number one seed in the NFC and a first-round bye.

They rebounded in the Wild Card round though, as they travelled to Philadelphia to down the Eagles, 23-19.

Seattle Seahawks Riding 7-Game Win Streak

Seattle ended the regular season on a seven-game win streak, securing the number one seed in the NFC and a Wild Card bye.

The Seahawks opened the season with a 17-13 defeat at home to division rivals San Francisco, but they rallied over the next several weeks to enter they bye week at 5-2.

They then returned to action with back-to-back wins, before suffering their final defeat of the regular season as they fell 21-19 at the Los Angeles Rams.

Seattle rebounded immediately with a 30-24 success at Tennessee, and that proved to be the start of a seven-game surge to end the regular season.

The Seahawks shut out Minnesota at home, 26-0, and followed up a 37-9 victory in Atlanta with home wins over Indianapolis, 18-16, and the Rams, 38-37 in overtime.

They then closed out the regular season with back-to-back road games, beating Carolina 27-10 and San Francisco 13-3.

Verdict

The Seahawks took the Week 18 meeting and we are expecting more of the same here.

San Francisco have done a tremendous job overcoming injuries this season, but losing George Kittle is a huge blow and Seattle were able to shut down the Niners a fortnight ago.

Best Bet1: Seattle -7.5 Spread @9/10 at Hollywood bets - 4 Units
Best Bet2: Under 45.5 Total Points @9/10 at bet365 - 2 Units
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