San Francisco 49ers at Seattle Seahawks Betting Tips – Take Niners & Points In Key NFL Matchup

Leigh Copson

Editor

Last updated: Thu 08 Oct 2026 13:51

Leigh Copson 49 minutes ago

Share this article

San Francisco are tipped to cover as underdogs, bringing a perfect 4-0 record
Seattle have won 3 of their first 4 games this season
Article expects a close matchup, recommending the 49ers and the points

(Getty Images)

San Francisco 49ers at Seattle Seahawks Betting Tips

Key Numbers – Will 49ers Take Record To 5-0?
Seahawks Lead All-Time Head-To-Head; Won Last Meeting
San Francisco 49ers Possess Perfect 4-0 Record
Seattle Seahawks Off To Strong Start With Three Wins

San Francisco are tipped to cover as a betting underdog in Seattle.

The Seahawks have the “12th Man” advantage, and they have largely looked good on both sides of the football through the first four weeks of the season.

But so have the 49ers, and they have all of the key pieces in place on the offense at this time.

Key Numbers – Will 49ers Take Record To 5-0?

San Francisco 49ers have won all 4 games so far
San Francisco 49ers have covered in 3 of their 4 games
San Francisco 49ers have won 4 of the last 5 meetings in Seattle
The Under has cashed in 3 of the previous 4 meetings

Seahawks Lead All-Time Head-To-Head; Won Last Meeting

Seattle Seahawks lead the all-time series 33-24
Seattle Seahawks won 13-3 when the two teams last met in January 2026

San Francisco 49ers Possess Perfect 4-0 Record

San Francisco head to the Pacific Northwest boasting a 100% record thanks to four consecutive victories.

The 49ers made the long trip to Australia for opening day, but they made it a worthwhile visit as they downed the Los Angeles Rams in Melbourne, 27-7.

They backed that up a week later in their home opener, as they made light work of Miami in a 35-13 victory.

That was the start of a run of three consecutive home games for San Francisco, and they have taken full advantage.

The 49ers knocked off another division rival as they beat Arizona 36-30, and that was followed by a 24-14 success when they hosted Denver last weekend.

Seattle Seahawks Off To Strong Start With Three Wins

Seattle go into this big NFC West clash having rebounded from their first defeat of the season to improve to 3-1.

The Seahawks – who won the Super Bowl last season – began their defence of the crown with a 13-10 win over New England.

They then backed that up in their road opener a week later, as they visited Arizona and blew out the Cardinals, 31-7.

Seattle failed to make it three-in-a-row as they were beaten 33-31 at Washington in Week 3, but they issued an immediate response to that.

The Seahawks got back to winning ways last Sunday as they beat the Los Angeles Chargers 30-23 at home.

Verdict

SF 49ers @ SEA Seahawks

Seattle are off to a solid start, but so are San Francisco thanks to a balanced offense and a tough defense.

This is likely to be a close matchup that goes down to the wire, so we are taking the 49ers and the free field goal.

San Francisco +3.0

Spread

@9/10 - 4 Units

Bet £10 Get £30

with bonus code NEWBONUS

Available to new customers only. Make a qualifying deposit of £5 or more and claim the offer within 30 days of registering your account to qualify for 300% of that amount in Bet Credits, up to a maximum of £30 in Bet Credits. Once released, your Bet Credits will be held in your account balance and are non-withdrawable. Min deposit requirement. Free Bets are paid as Bet Credits and are available for use upon settlement of qualifying bets. Min odds, bet and payment method exclusions apply. Returns exclude Bet Credits stake. Registration required. Time limits and T&Cs apply. The bonus code NEWBONUS can be used during registration but does not change the offer amount in any way. #ad

Bet at bet365

Under 45.5

Total Points

@9/10 - 2 Units

Bet £10 Get £10

Promo Code: NEWBONUS

New customers only. Bet £10+ to receive £10 in Free Bets. 7-day free bet expiry. Stake not returned. Promotional Terms Apply. 18+. GambleAware.org

Bet at dabble

US sports writer covering the NFL, NBA, NHL, boxing and MMA, with previews, predictions and betting tips across the major American leagues.

During his career at the Press Association and online sports sites including FreeTips and ExpertPicks.com, he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final.

He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.

Follow more of Leigh's work on Muckrack and connect with him on LinkedIn.