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Las Vegas Raiders at San Francisco 49ers Betting Tips – 49ers To Bounce Back In NFL

leigh-copson
Editor
Last updated: Wed 04 Nov 2026 12:13
The San Francisco 49ers are tipped to cover the spread against the Las Vegas Raiders as they return from a bye week aiming to bounce back from their first defeat of the season. The 49ers have won six of their first seven games and all four home fixtures, while the Raiders rank 31st in the NFL for points allowed per game and have seen the Over land in each of their last six matches. The 49ers’ offence is expected to capitalise on the Raiders’ defensive struggles, with a double-digit victory predicted.
Leigh Copson 3 hours ago
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  • San Francisco tipped to cover spread against Raiders
  • 49ers’ offense faces a Raiders defense ranked 31st in points allowed per game
  • San Francisco return from a bye week after their first loss of the season
(Getty Images)

San Francisco are tipped to cover as they return to winning ways.

The 49ers slipped up in Atlanta, but the bye week has given them extra time to prepare for this one, and the offense should have few issues piling up points against a bad Raiders defense.

Key Numbers – Can Niners Go 7-1 In NFL?

  • San Francisco 49ers have won 6 of their first 7 games
  • San Francisco 49ers have won all 4 of their home games
  • Las Vegas Raiders are 31st in the NFL in points allowed per game
  • The Over has cashed in each of Las Vegas’ last 6 games

49ers Lead All-Time Head-To-Head; Won Last Meeting

  • San Francisco 49ers lead the all-time series 8-7
  • San Francisco 49ers won 37-34 in overtime when the two teams last met in January 2023

Las Vegas Raiders Ended Four-Game Skid Last Week

Las Vegas go into this matchup having ended a four-game losing run last weekend, improving their record to 4-4.

The Raiders made a flying start to the season as they won their first three games, starting with a 27-13 victory at home to Miami.

They then backed that up on the road as they downed the Los Angeles Chargers, 26-14, and New Orleans, 35-27.

Las Vegas went cold after that though, as they lost 30-27 to Kansas City, 45-17 at New England, 33-30 to Buffalo and 35-21 to the Los Angeles Chargers.

The Raiders finally stopped the rot last weekend, as they got back to .500 with a 38-33 win at the New York Jets.

San Francisco 49ers Suffered First Loss Last Time Out

San Francisco return from the bye week looking to bounce back from their first defeat of the season, which dropped them to 6-1.

The 49ers made the long trip to Australia for the season-opener, but made it a worthwhile visit as they beat the Los Angeles Rams 27-7.

They then built on that success at home as they beat Miami 35-13, Arizona 36-30 and Denver 24-14.

San Francisco made it five-in-a-row as they went out on the road to beat Seattle 32-29, and made it six straight as they returned home to beat Washington 23-17.

The 49ers failed to make it to 7-0 however, as they suffered a surprise 29-20 defeat in Atlanta last time out.

Verdict

That loss in Atlanta was a bad one for San Francisco, but nobody in the 49ers camp will be panicking.

This Las Vegas defense is there for the taking, and we expect Brock Purdy & Co. to take full advantage as the 49ers win the game by double digits.

Best Bet1: San Francisco -9.5 Spread @9/10 at bet365 - 4 Units
Best Bet2: Over 52.5 Total Points @9/10 at Star Sports - 2 Units
San Francisco -9.5
Spread
@9/10 - 4 Units
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Bet at bet365
Over 52.5
Total Points
@9/10 - 2 Units
Bet £20 Get £10
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Bet at Star Sports
leigh-copson
Leigh Copson

Sports Editor • 25+ Years Experience, US & Combat Sports Specialist

US sports writer covering the NFL, NBA, NHL, boxing and MMA, with previews, predictions and betting tips across the major American leagues.

During his career at the Press Association and online sports sites including FreeTips and ExpertPicks.com, he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final.

He has also covered almost every major boxing match and UFC fight card during this time. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.

Follow more of Leigh's work on Muckrack and connect with him on LinkedIn.

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