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Hoffenheim vs Lyon Predictions & Betting Tips - Value on the Visitors in the Europa League

eddy-tora
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Last updated: Wed 21 Oct 2026 15:59
Lyon travel to face Hoffenheim in the Europa League, with the French side favored due to impressive form and top standing in Ligue 1. Hoffenheim have been struggling defensively, losing four of their last five matches and conceding heavily at home. Lyon have won both Europa League games so far, and their attacking strength is expected to exploit Hoffenheim’s issues. The article recommends backing Lyon to win in a high-scoring contest, highlighting bets on a Lyon victory, both teams to score, and over 3.5 goals.
Eddy Tora 1 hour ago
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  • Hoffenheim come into this clash in poor form
  • Lyon currently sit top of the table in Ligue 1
  • I am backing the visitors in the Europa League
Lyon
Lyon currently top the table in Ligue 1 (Getty)

Hoffenheim are in a relegation battle in the Bundesliga and Lyon are top of Ligue 1. It makes sense to back the visitors to win a high scoring clash in the Europa League.

Key Stats


  • Hoffenheim have seen BTTS in 7 of their last 8 matches.
  • Hoffenheim have lost 6 of their last 8 matches.
  • Hoffenheim have seen over 3.5 goals in 8 of their last 12 matches.
  • Lyon have seen BTTS & over 3.5 goals in 3 matches against Hoffenheim.
  • Lyon have seen BTTS in 4 of their last 5 matches.
  • Lyon have won 4 of their last 5 matches.

HTH


These clubs have met three times with event encounter ending in a high scoring draw.

Relegation Concerns for Hoffenheim


Hoffenheim are in poor form having lost four of their previous five matches. Two of those came in the Europa League, 2-0 at OFI Crete and 3-2 against Besiktas.

Christian Ilzer is under huge pressure with his side leaking goals at an alarming rate. Playing at home is not having a positive effect, conceding 10 goals in four games in Sinsheim.

Ilzer saw his side win 2-1 at Borussia Monchengladbach on Sunday. It wasn’t easy against the worst team in the Bundesliga, Alexander Prass assisting Bambasé Conté before scoring to get his side out of the relegation zone.

Lyon Flying High in France


Lyon have been hard to beat this season and currently sit top of Ligue 1. They have won both matches in the Europa League, 2-1 at Anderlecht and 3-2 against Crystal Palace.

Paulo Fonseca’s side are coming off a 2-1 win against Nice. Pavel Sulc and Tanner Tessmann scored to erase an early deficit and they held on after Keito Nakamura was sent off in the 70th minute.

Predicted Lineups & Team News


Hoffenheim (4-2-3-1): Oliver Baumann; Vladimír Coufal, Robin Hranác, Ozan Kabak, Bernardo; Leon Avdullahu, Wouter Burger; Bambasé Conté, Andrej Kramarić, Alexander Prass; Fisnik Asllani

Centre-back Albian Hajdari is out with a foot injury. Midfielder Nathan De Cat has a meniscus problem and winger Patrick Wimmer is dealing with a hamstring injury.

Ozan Kabak and Mats Rots could replace Koki Machida and Bernardo in the defensive line. Expect Wouter Burger and Andrej Kramarić to return to the starting side here.

Lyon (4-3-1-2): Dominik Greif; Zachary Athekame, Felix Bacher, Ruben Kluivert, Abner Vinícius; Noah Nartey, Tyler Morton, Corentin Tolisso; Pavel Sulc; Ernest Nuamah, Keito Nakamura

Left-backs Nicolás Tagliafico and Mohamed Ouédraogo are injured with Abner Vinicius to continue in the starting side.

Verdict

Hoffenheim have been far from convincing despite proving they can score goals. Their defensive issues can be exploited by a Lyon side that are playing with confidence.

Best Bet1: BTTS Yes & Over 3.5 BTTS & Total Goals @6/4 at bet365 - 3 Units
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eddy-tora
Eddy Tora

Sports Editor • 15+ Years of Experience, Football & Tennis Betting Specialist

Eddy writes about a number of sports with a strong focus on European football and tennis.

  
You will find him covering big football matches from around Europe and beyond as well as ATP Tour tennis.

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