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Inter Milan vs Shakhtar Donetsk Tips & Predictions – Nerazzurri to Bounce Back in the Champions League

vedran-ostojic
Editor
Last updated: Mon 19 Oct 2026 19:45
Inter Milan are expected to defeat Shakhtar Donetsk at home on Wednesday, having won four of their five home matches this season. The Italian side has kept five consecutive clean sheets against the Ukrainian visitors. The article recommends a home win to nil as the best bet. Additionally, with Lautaro Martinez injured, Marcus Thuram is likely to lead the attack and is a promising candidate to score at any time.
Vedran Ostojic 1 hour ago
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  • Inter Milan are in a must-win situation after losing their first two games
  • We are backing them to collect points on Wednesday
  • Check our ful preview for Inter Milan vs Shakhtark Donetsk below
Inter Milan have won 4 of their last 5 home matches (Getty)

Inter Milan are in a must-win situation after losing the opening two UCL games in which they missed an absurd number of chances. I expect them to be focused and claim a clean win against Shakhtar on Wednesday. 

Key Stats  


  • Inter Milan have won 4 of their last 5 home matches. 
  • Inter Milan have kept a clean sheet in their last 5 matches against Shakhtar Donetsk. 
  • Inter Milan’s Marcus Thuram has scored 2 goals in his last 3 matches. 
  • Shakhtar Donetsk have lost 5 of their last 7 away matches (UCL). 

Shakhtar Winless Against Inter 


These clubs locked horns seven times so far, Inter Milan winning on three occasions while four encounters ended without a winner.  

Nerazzurri Desperate for Points 


Inter Milan have no room for mistake anymore after starting the UCL main phase with back to back defeats against Real Madrid 2-1 in Spain and 4-3 against Club Brugge at home last week. 

Cristian Chivu’s side was brutally punished for missed opportunities by Brugge, ending this clash with 30-18 shots and 4.33-4.28 expected goals. Lautaro Martinez netted a brace, Ange Bonny also on target. 

Nerazzurri returned to winning ways last weekend on a tough trip, beating Bologna 3-1. Once again they created an absurd number of goal chances and posted high xG of 3.16. This victory kept them top of the Serie A table with 19 points after seven rounds. 

Shakhtar Unbeaten After Two Rounds 


Shakhtar Donetsk left a solid impression in their opening UCL main stage match, snatching a point against PSV 1-1 in Eindhoven despite being tagged underdogs here, limiting opposition to just two shots on target. 

Last week, they were nominal hosts against AEK Athens on neutral ground in London and claimed a 3-1 victory, scoring two late goals. The Miners had 1.36-1.34 xG and 4-3 shots on target here. 

Last weekend, Arda Turan’s side extended their domestic winning run to five games by defeating Kolos Kovalivka 2-1 in the Ukrainian Premier League which kept them top of the table (eight wins, one loss so far). 

Team News & Predicted Lineups 


Inter Milan (3-5-2) Josep Martinez; Yann Bisseck, Manuel Akanji, Alessandro Bastoni; Andy Diouf, Nicolo Barella, Hakan Calhanoglu, Henrikh Mkhitaryan, Federico Dimarco; Marcus Thuram, Pio Esposito

Inter Milan enter the fixture managing important squad absences, as captain Lautaro Martinez remains sidelined alongside John Stones, Benjamin Pavard, and Curtis Jones.

Shakhtar Donetsk (4-2-3-1) Dmytro Riznyk; Vinicius Tobias, Valeriy Bondar, Mykola Matviyenko, Pedro Henrique; Oleh Ocheretko, Marlon Gomes; Alisson Santana, Pedrinho, Newerton; Kaua Elias

Eguinaldo and Alaa Ghram are injured for the Ukrainian champions, while Marlon Santos and Diego Arroyo remain major doubts.

Verdict

Inter Milan have won four of their five home matches this season and I expect them to beat Shakhtar Donetsk on Wednesday. Nerazzurri also kept five clean sheets in a row against the Ukrainian side, so a home win to nil is my best bet. 

Another bet worth considering is Marcus Thuram to score anytime. He is almost certain to lead the attack since Lautaro Martinez is injured and his recent form has been good. 

Best Bet1: Inter Milan To Win to Nil @6/5 at bet365 - 2 Units
Best Bet2: Marcus Thuram Anytime Goalscorer @7/10 at dabble - 2 Units
Best Bet3: Marcus Thuram First Goalscorer @7/2 at Star Sports - 1 Unit
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vedran-ostojic
Vedran Ostojic

Sports Editor • 10+ Years Of Experience in Football, Basketball, Handball & Volleyball

Vedran is a passionate sports enthusiast and covers European football, basketball, volleyball and handball.


With a particular love for the English Premier League, he's been writing about sports online for more than a decade since completing a degree in literature and sports journalism.

The primary areas of focus include top European football leagues (mainly EPL, La Liga, Serie A & Bundesliga), basketball (EuroLeague, NBA & WNBA), Handball and Volleyball.

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