Indianapolis Colts at Minnesota Vikings Betting Tips – Vikings To Stay Unbeaten In NFL

Leigh Copson

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Last updated: Wed 21 Oct 2026 16:08

Leigh Copson 3 hours ago

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Minnesota are 5-0, with dominant defense allowing just 12.8 points per game
Indianapolis have dropped to 2-4 after consecutive losses
Vikings favoured to cover spread and extend perfect start to 6-0

(Getty Images)

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Indianapolis Colts at Minnesota Vikings Betting Tips

Key Numbers – Will Vikings Improve To 6-0?
Colts Lead All-Time Head-To-Head; Vikings Won Last Meeting
Indianapolis Colts 2-4 Following Back-To-Back Losses
Minnesota Vikings Boast Perfect 5-0 Record

Minnesota are tipped to cover the spread as they keep their unbeaten record intact.

The Vikings can once again lean on Brian Flores’ dominant defense, while the offense puts in another complementary performance to deliver victory and a cover.

Key Numbers – Will Vikings Improve To 6-0?

Minnesota Vikings have won all 5 of their games so far
Minnesota Vikings have covered in 4 of their first 5 games
Indianapolis Colts have failed to cover in 3 of their 4 defeats
The Under has cashed in each of Minnesota’s last 4 games

Colts Lead All-Time Head-To-Head; Vikings Won Last Meeting

Indianapolis Colts lead the all-time series 18-9-1
Minnesota Vikings won 21-13 when the two teams last met in November 2024

Indianapolis Colts 2-4 Following Back-To-Back Losses

Indianapolis head to Minnesota looking to rebound from back-to-back defeats that have dropped them to 2-4.

The Colts kicked off the season with a 41-23 defeat to Baltimore, and were then beaten 33-30 in overtime when they visited Indianapolis.

They finally got off the mark in Week 3 as they edged Houston at home, 19-17, and they followed that up a week later with a 33-13 success at Washington.

However, Indianapolis failed to make it three-in-a-row as they were beaten 34-22 in Pittsburgh.

That became back-to-back defeats for the Colts last weekend, as they suffered a 26-20 defeat at previously winless Tennessee.

Minnesota Vikings Boast Perfect 5-0 Record

Minnesota return from the bye week as one of just three teams boasting a 100% record after the first six weeks.

The Vikings kicked off the campaign in the best possible fashion as they downed division rivals Green Bay, 39-22.

They backed that up on the road a week later, as they knocked off another NFC North foe, beating Chicago 9-3.

Minnesota’s perfect start continued in Tampa as they beat the Buccaneers 23-16, and they followed that up at home as they saw off Miami 15-10.

The Vikings then made it five-in-a-row before the bye week, as they went out on the road to beat New Orleans 23-13.

Verdict

IND Colts @ MIN Vikings

Minnesota’s unbeaten start has been massively down to a defense that has allowed just 12.8 points per game.

That unit can cause more problems for Daniel Jones and the Colts, ensuring the Vikings cover the spread as they reach 6-0.

Minnesota -6.5

Spread

@9/10 - 4 Units

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Bet at bet365

Under 41.5

Total Points

@9/10 - 2 Units

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US sports writer covering the NFL, NBA, NHL, boxing and MMA, with previews, predictions and betting tips across the major American leagues.

During his career at the Press Association and online sports sites including FreeTips and ExpertPicks.com, he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final.

He has also covered almost every major boxing match and UFC fight card during this time. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.

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