Buffalo Bills at Houston Texans Betting Tips – Back Bills For Week 1 Victory In NFL

Leigh Copson

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Last updated: Wed 09 Sep 2026 12:39

Leigh Copson 2 hours ago

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Bills expected to cover -1.5 spread on the road vs Texans
Texans lead all-time series 7-5; won last meeting
Recommended bets: Bills -1.5 & Under 44.5 points

(Getty Images)

Buffalo Bills at Houston Texans Betting Tips

Key Numbers – Will Bills Continue Trend From 2025?
Texans Lead All-Time Head-To-Head; Won Last Meeting
Buffalo Bills Fell Short In 2025 Playoffs
Houston Texans Made Playoffs Last Season

Buffalo are tipped to cover as they win on the road in Houston.

The Bills defense can cause plenty of problems for CJ Stroud, while Josh Allen leans on the run game and also turns to new number one receiver DJ Moore in critical moments.

Key Numbers – Will Bills Continue Trend From 2025?

All 13 of Buffalo Bills’ wins last season were by 2+ points
Houston Texans have failed to cover in their last 3 season openers
The Under has cashed in 4 of the previous 5 meetings

Texans Lead All-Time Head-To-Head; Won Last Meeting

Houston Texans lead the all-time series 7-5
Houston Texans won 23-19 when the two teams last met in November 2025

Buffalo Bills Fell Short In 2025 Playoffs

Buffalo once again came up short in the playoffs last time around, costing Sean McDermott his job as head coach.

Once again the Bills went into a campaign as a leading contender to lift the Vince Lombardi Trophy, and they made a strong start as they won six of their first eight games.

They then wobbled in November, losing a couple of road games, but rebounded with a 5-1 run to close out the regular season with a 12-5 record.

Buffalo then fended off Jacksonville in the Wild Card round, 27-24, only to bow out in the Divisional round as they lost 33-30 in overtime in Denver.

The Bills warmed up for the new season by going 3-0 in pre-season, sandwiching a 31-7 victory in Cleveland with home wins over Carolina, 29-14, and Pittsburgh, 28-27.

Houston Texans Made Playoffs Last Season

Houston enter the new season with their sights set on another run in the postseason, having bowed out in the Divisional round last time around.

The Texans made a miserable start to the season as they lost their first three games, and found themselves sitting at 3-5 in early November.

They got hot after that though, reeling off nine consecutive wins to finish second in the AFC South with a 12-5 record.

Houston then blew out Pittsburgh in the Wild Card round, winning 30-6, only to lose 28-15 when they visited New England a week later.

The Texans go into the new campaign having lost all three preseason matchups, falling 27-7 to the Los Angeles Chargers, 22-20 to Las Vegas, and 16-13 in Carolina.

Verdict

BUF Bills @ HOU Texans

Houston have been something of a bogey team to Buffalo in recent years, but we are backing the Bills to exorcise a few demons here.

In what is likely to be a close game, we are backing Josh Allen to make more plays than CJ Stroud as the Bills escape with the dub.

Buffalo -1.5

Spread

@20/21 - 4 Units

Bet £10 Get £30

with bonus code NEWBONUS

Available to new customers only. Make a qualifying deposit of £5 or more and claim the offer within 30 days of registering your account to qualify for 300% of that amount in Bet Credits, up to a maximum of £30 in Bet Credits. Once released, your Bet Credits will be held in your account balance and are non-withdrawable. Min deposit requirement. Free Bets are paid as Bet Credits and are available for use upon settlement of qualifying bets. Min odds, bet and payment method exclusions apply. Returns exclude Bet Credits stake. Registration required. Time limits and T&Cs apply. The bonus code NEWBONUS can be used during registration but does not change the offer amount in any way. #ad

Bet at bet365

Under 44.5

Total Points

@9/10 - 2 Units

Bet £10 Get £10

Promo Code: NEWBONUS

New customers only. Bet £10+ to receive £10 in Free Bets. 7-day free bet expiry. Stake not returned. Promotional Terms Apply. 18+. GambleAware.org

Bet at dabble

During his career he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final. He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.

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