Buffalo Bills at Las Vegas Raiders Betting Tips – Bills To Leave Las Vegas With NFL Win

Leigh Copson

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Last updated: Thu 15 Oct 2026 11:18

Leigh Copson 2 hours ago

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Buffalo favored to win and cover spread against Las Vegas
Buffalo leads the all-time series 22-21 and dominated last meeting in September 2023
Las Vegas have lost their last two games after opening the season 3-0

(Getty Images)

Buffalo Bills at Las Vegas Raiders Betting Tips

Key Numbers – Can Bills Improve To 5-1?
Bills Lead All-Time Head-To-Head; Won Last Meeting
Buffalo Bills 4-1 Following Overtime Win
Las Vegas Raiders Cooled Off With Back-To-Back Losses

Buffalo are tipped to cover as they win on the road in Las Vegas.

Both defenses have given up a bunch of points this season, so in what could turn into a shootout, you have to go with Josh Allen over Kirk Cousins, who was benched in last weekend’s loss.

Key Numbers – Can Bills Improve To 5-1?

Buffalo Bills have won 4 of their 5 games so far
Buffalo Bills have covered in all 4 of their wins this season
Las Vegas Raiders have lost their last 2 games
The Over has cashed in 4 of Buffalo’s 5 games this season

Bills Lead All-Time Head-To-Head; Won Last Meeting

Buffalo Bills lead the all-time series 22-21
Buffalo Bills won 38-10 when the two teams last met in September 2023

Buffalo Bills 4-1 Following Overtime Win

Buffalo head to Las Vegas having improved their record to 4-1 with an overtime win at Super Bowl favourites, the Los Angeles Rams.

The Bills kicked off the season with a trip to Houston, and enjoyed a winning start as they downed the Texans, 36-31.

A week later they marked their first competitive game at their new stadium with a 41-31 win over Detroit, and backed that up by beating the Los Angeles Chargers, 24-16.

Buffalo failed to make it four-in-a-row as they were beaten at home by division rivals New England, 29-26, but they rebounded immediately.

The Bills got back to winning ways last Monday night as they downed the Rams on the road, 37-34 in overtime.

Las Vegas Raiders Cooled Off With Back-To-Back Losses

Las Vegas come into this matchup have now lost back-to-back games to fall to 3-2 through five weeks.

The Raiders opened the campaign with a 27-13 victory over Miami, and that proved to be the start of a three-game win streak.

They went out on the road over the next two weeks and beat the Los Angeles Chargers 26-14, and New Orleans 35-27.

Las Vegas were unable to reach 4-0 though, as they were beaten 30-27 at home by AFC West rivals Kansas City.

The Raiders then followed that up with a 45-17 blowout loss when they visited New England last weekend.

Verdict

BUF Bills @ NO Saints

Back-to-back road games on the opposite side of the country is tough, but Buffalo are more than capable of recording another victory.

Josh Allen can have his way with this Raiders defense to ensure Buffalo win the game and cover the spread in the process.

Buffalo -5.5

Spread

@9/10 - 4 Units

Bet £10 Get £30

with bonus code NEWBONUS

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Bet at bet365

Over 53.5

Total Points

@9/10 - 2 Units

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US sports writer covering the NFL, NBA, NHL, boxing and MMA, with previews, predictions and betting tips across the major American leagues.

During his career at the Press Association and online sports sites including FreeTips and ExpertPicks.com, he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final.

He has also covered almost every major boxing match and UFC fight card during this time. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.

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