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Chicago White Sox at Cleveland Guardians Betting Tips – Underdog Sox To Win Again In MLB

leigh-copson
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Last updated: Tue 15 Sep 2026 08:35
The Chicago White Sox are tipped to secure back-to-back wins over the Cleveland Guardians following a strong offensive showing and improved performance from pitcher Davis Martin. Chicago has claimed 7 of their last 11 meetings this season, while Cleveland has lost 12 of their last 20 home games and continues to struggle for consistency. With Cleveland's Foster Griffin having a tough start for the Guardians, the White Sox are a solid underdog bet—consider the Moneyline at 2.20. The Over on total runs (7.0) at 1.96 also looks attractive given recent trends.
Leigh Copson 1 hour ago
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  • White Sox are backed to win as underdogs after impressive recent performance
  • Cleveland's Foster Griffin has struggled since joining, making them vulnerable
  • Recommended bets: Chicago Moneyline (2.20) & Over 7.0 total runs (1.96)
(Getty Images)

Chicago are tipped to win as an underdog for the second straight day in Cleveland.

Davis Martin has been in improved form for the White Sox recently, while the visitors can build on last night’s strong offense showing Foster Griffin, who has struggled since joining the Guardians.

Key Numbers – Can Chicago Go 8-4 vs Cleveland?

  • Chicago White Sox have won 7 of the previous 11 meetings this season
  • Cleveland Guardians have lost 12 of their last 20 home games
  • Davis Martin has a 5.94 ERA since joining Cleveland Guardians
  • The Over has cashed in 4 of the previous 5 meetings

Guardians Lead All-Time Head-To-Head; White Sox Won Last Meeting

  • Cleveland Guardians lead the all-time series 1139-1138-17
  • Chicago White Sox won 7-3 when the two teams last met on September 14

Chicago White Sox Form – Last 10 Games

Chicago go into the second game of this series having lost six of their last 10, but having beaten the Guardians 7-3 in Monday's series opener.

DateOppositionW/LScore
Sep-04 vs Minnesota Twins W 4-1
Sep-05 vs Minnesota Twins L 4-6
Sep-06 vs Minnesota Twins W 10-1
Sep-08 vs Pittsburgh Pirates L 3-9
Sep-09 vs Pittsburgh Pirates L 2-4
Sep-10 vs Pittsburgh Pirates L 0-2
Sep-11 at St Louis Cardinals L 3-7
Sep-12 at St Louis Cardinals W 6-5
Sep-13 at St Louis Cardinals L 1-3
Sep-14 at Cleveland Guardians W 7-3

Cleveland Guardians Form – Last 10 Games

Cleveland enter this matchup having split their previous 10 games overall, and having not won consecutive games since September 4.

DateOppositionW/LScore
Sep-04 vs Detroit Tigers W 4-3 W/O
Sep-05 vs Detroit Tigers L 0-6
Sep-06 vs Detroit Tigers W 3-2 W/O
Sep-07 at Baltimore Orioles L 4-6
Sep-08 at Baltimore Orioles W 9-5
Sep-09 at Baltimore Orioles L 5-9
Sep-11 at Minnesota Twins W 5-2
Sep-12 at Minnesota Twins L 3-4
Sep-13 at Minnesota Twins W 9-2
Sep-14 vs Chicago White Sox L 3--7

Starting Pitchers

PlayerTeamRecordERAStrikeoutsInnings
Davis Martin Chicago White Sox 9-7 4.05 115 135.2
Foster Griffin Cleveland Guardians 15-5 3.65 146 162.2

Verdict

Chicago delivered as an underdog on Monday and we like their chances of repeating here.

Griffin has had a tough time since making the move from Washington to Cleveland, making this a good opportunity for the White Sox bats to back up yesterday’s seven-run showing.

Best Bet1: Chicago Win Moneyline @21/20 at bet365 - 4 Units
Best Bet2: Over 8.5 Total Runs @6/7 at dabble - 2 Units
Chicago Win
Moneyline
@21/20 - 4 Units
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Bet at bet365
Over 8.5
Total Runs
@6/7 - 2 Units
Bet £10 Get £10
Promo Code: NEWBONUS

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Bet at dabble
leigh-copson
Leigh Copson

Sports Editor • 25+ Years Experience, US & Combat Sports Specialist

During his career he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final. He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.


Follow more of Leigh's work on Muckrack.

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