Michigan State at Notre Dame Betting Tips – Fighting Irish To Stay Perfect In College Football

Leigh Copson

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Last updated: Wed 16 Sep 2026 12:34

Leigh Copson 1 hour ago

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Notre Dame is 2-0, with two blowout wins and covers
Irish tipped to cover -29.5 vs. undefeated Michigan State
Recommendation: Notre Dame to cover & under 52.5 points

(Getty Images)

Michigan State at Notre Dame Betting Tips

Key Numbers – Can Fighting Irish Record 3rd Straight Cover?
Notre Dame Lead All-Time Head-To-Head; Won Last Meeting
Michigan State Take 100% Record To South Bend
Notre Dame Unbeaten After First Two Games

Notre Dame are tipped to cover a big spread as they improve to 3-0.

The Fighting Irish are firing offensively with CJ Carr at the controls, and this defense has already put the clamps on two opponents this season and can do the same to the Spartans.

Key Numbers – Can Fighting Irish Record 3rd Straight Cover?

Notre Dame have covered in each of their first two games
Notre Dame have won their first two games by an average of 40 points per game
Notre Dame have covered in 5 of their last 7 home games as a double digit favourite
The Under cashed in both teams’ Week 2 matchups

Notre Dame Lead All-Time Head-To-Head; Won Last Meeting

Notre Dame lead the all-time series 49-29-1
Notre Dame won 38-18 when the two teams last met in September 2017

Michigan State Take 100% Record To South Bend

Michigan State head out on the road for the first time this season having opened with back-to-back wins.

The Spartans have faced a couple of opponents from the Mid-American conference, winning both games by double digits.

They opened up with a 30-20 victory over Toledo, and backed that up with a 35-7 blowout of Eastern Michigan last weekend.

Quarterback Alessio Milivojevic went 12/20 for 170 yards and two touchdowns, with Charles Taplin accounting for 65 receiving yards and a score.

Camryn Edwards was the star performer on the day for Michigan State, as he racked up 152 rushing yards and a couple of touchdowns.

Notre Dame Unbeaten After First Two Games

Notre Dame enter this matchup boasting a perfect record thanks to a couple of blowout victories.

The Fighting Irish opened up the campaign by facing Wisconsin at Lambeau Field, and ran out 41-13 winners.

They followed that up with another one-sided win in their home opener, as they shut out Rice in a 52-0 victory.

CJ Carr went 16/20 for 253 yards and four touchdowns before exiting the game, and by the end of the game 12 different players had caught a pass.

Jonaz Walton led the team in rushing with 48 yards off eight carries, while Nolan James Jr turned two of his seven touches into touchdowns.

Verdict

Michigan State @ Notre Dame

Notre Dame have blown out their first two opponents, and more of the same is expected here.

Another efficient offensive performance and dominant defensive display can ensure a win and cover for the Fighting Irish.

Notre Dame -29.5

Spread

@9/10 - 4 Units

Bet £10 Get £30

with bonus code NEWBONUS

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Bet at bet365

Under 52.5

Total Points

@9/10 - 2 Units

Bet £10 Get £10

Promo Code: NEWBONUS

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During his career he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final. He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.

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