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Syracuse at Pitt Betting Tips – Panthers To Cover In College Football Conference Win

leigh-copson
Editor
Last updated: Wed 16 Sep 2026 10:39
Pitt is set to host Syracuse in their ACC opener after starting the season 2-0. Syracuse arrives on the heels of their first loss, struggling offensively and with discipline issues. Pitt, who has dominated the series and covered the spread in most matchups, is tipped to cover again thanks to a strong run game and solid defense. With home advantage and recent momentum, the Panthers are recommended to continue their winning ways if they minimize mistakes.
Leigh Copson 2 hours ago
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  • Pitt opens ACC play at 2-0, favoured to cover vs. Syracuse
  • Syracuse struggled in last game with turnovers and penalties
  • Panthers' defense and home advantage tip the scales
(Getty Images)

Pitt are tipped to cover as they maintain their perfect record and win their ACC opener.

The Panthers’ stout run game can force Steve Angeli to try to win this with his arm – a potential recipe for disaster for the visitors after he threw three picks in last week’s loss to Cal.

Key Numbers – Can Pitt Go 3-0?

  • Pitt have won their first 2 games of the season
  • Syracuse failed to cover as they lost their ACC opener
  • Pitt have won 7 of the previous 8 meetings
  • Pitt have covered in 8 of the previous 10 meetings
  • The Under has cashed in 6 of the previous 7 meetings

Pitt Lead All-Time Head-To-Head; Won Last Meeting

  • Pitt lead the all-time series 45-33-3
  • Pitt won 30-13 when the two teams last met in October 2025

Syracuse Suffered First Defeat Last Weekend

Syracuse head to Pitt on a short week and on the back of their first defeat of the 2026 season.

The Orangemen kicked off their campaign with a 66-3 non-conference win over New Hampshire, but failed to follow that up in their opening ACC encounter.

They played host to Cal last weekend, and suffered a 21-18 defeat at the hands of the Golden Bears.

Quarterback Steve Angeli completed less than 50% of his 50 passing attempts, and racked up three interceptions in the loss.

An ill-disciplined performance all round saw Syracuse commit 14 penalties for a total of 110 yards.

Pitt Take Perfect 2-0 Record Into ACC Opener

Pitt go in their first conference matchup of the season having opened with back-to-back non-conference successes.

The Panthers recorded a blowout victory as they downed Miami Ohio 59-14 in their opening game.

They then backed that up last weekend as they scraped past UCF, beating their opposition from the Big 12, 12-7.

Quarterback Mason Heintschel went 18/29 for 212 yards, with Cataurus Hicks on the receiving end of 64 of those yards.

Damon Ferguson led the way on the ground, carrying the ball 20 times for 59 yards and a touchdown, while adding 27 yards receiving.

Verdict

Both teams are coming off underwhelming performances, but Pitt did win and they have home advantage on a short week.

If the offense can keep things clean, the Panthers can lean on their defense to get the job done.

Best Bet1: Pitt -10.5 Spread @9/10 at bet365 - 4 Units
Best Bet2: Under 51.5 Total Points @9/10 at dabble - 2 Units
Pitt -10.5
Spread
@9/10 - 4 Units
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Bet at bet365
Under 51.5
Total Points
@9/10 - 2 Units
Bet £10 Get £10
Promo Code: NEWBONUS

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Bet at dabble
leigh-copson
Leigh Copson

Sports Editor • 25+ Years Experience, US & Combat Sports Specialist

During his career he has covered some of the biggest sporting events on the planet, including the Super Bowl, the Champions League Final and the World Cup Final. He has also covered almost every major boxing match and UFC fight card during this time.. His specialist sports are American Football, Basketball, Ice Hockey, Boxing, Mixed Martial Arts and Football.


Follow more of Leigh's work on Muckrack.

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